Although EPC stands for Earnings per Click, in most cases, it shouldnt be taken literally. Instead, marketers use this term more commonly to talk about the earnings made by one hundred clicks. What this means is that sometimes EPC (Earnings per Click) and EPHC (Earnings per Hundred Clicks) are one and the same. EPC is calculated by taking the average of all traffic sent from the affiliate partner to the merchant, in a specific period of time. What this basically means is that the EPC is an average amount that an affiliate program pays to the publisher for each 100 clicks generated on the website.